Leukemoid Reaction as a “Tumor Marker” in Breast Cancer
نویسندگان
چکیده
منابع مشابه
Leukemoid Reaction as a “Tumor Marker” in Breast Cancer
Neutrophilic leukocytosis above 50 × 10/l exclude leukemia, defines a leukemoid reaction (LR). It is associated with several diseases. Although it simulates leukemia, most of the causes are benign. Tumor-related LR is more common. It is associated with ranulocyte colony-stimulating factor (G-CSF) secreted by the tumor cells. A 38-year-old woman, presented with advanced breast cancer and leukocy...
متن کاملEvaluating the Expression of Oct4 as a Prognostic Tumor Marker in Bladder Cancer
Objective(s)The key transcriptional regulator Oct4 is one of the self-renewal and differentiation-related factors in cancer stem cells, where it maintains "stemness" state. Cancer stem cells have been identified in a variety of solid malignancies. They are a small population of tumor cells with stem cell characteristics, which are a likely cause of relapse in cancer patients. Due to high incide...
متن کاملLeukemoid reaction in lung cancer patients.
[a] Biopsy proven poorly differentiated large cell carcinoma of the lung in a 61 year old woman. CT image of the chest with intravenous contrast medium at the level of the aortic arch shows right lung tumor (arrow), 6 cm, with central necrosis. [B] Photomicrograph of the lung showing atypical large cells with abundant eosinophilic cytoplasm and enlarged nuclei consistent with large cell type, u...
متن کاملLeukocyte Adhesion Deficiency Type 1 Presenting as Leukemoid Reaction
The hallmarks of leukocyte adhesion deficiency (LAD) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. These molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. Over las...
متن کاملIs Bax/Bcl-2 Ratio Considered as a Prognostic Marker with Age and Tumor Location in Colorectal Cancer?
Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Surgical Science
سال: 2012
ISSN: 2157-9407,2157-9415
DOI: 10.4236/ss.2012.35054